https://www.cbc.ca/radio/quirks/beyond-long-covid-1.7485888

“There is no such thing as a COVID infection without consequence,” says long COVID researcher, David Putrino[…].

So there is a cumulative effect that can be occurring with each infection.

Early in the pandemic, we actually published a paper where we showed that, even in animal models — when we infected mice with a very, very mild case of SARS-CoV-2 infection — which only caused lung inflammation, we still saw these inflammatory chemicals called chemokines emerging from the infected lungs and starting to attack central nervous system structures such as the spinal cord and the brain.

[…]You know, this is a virus that, once it enters the body, is very capable of entering the bloodstream, creating immune responses that travel all over the body.

It disrupts what we call “interferon signalling,” which is part of the immune system that helps you to fight off infections or latent infections, such as Epstein Barr virus.

Typically our immune system can keep these things suppressed, but when SARS-CoV-2 enters the picture, it starts to cause altered interferon signalling. It causes immune damage and dysregulation.

And suddenly, not only does your body have trouble clearing the SARS-CoV-2 virus itself, but it also starts to have trouble keeping some of these other viruses that have been latent from reactivating and causing problems.

In addition to SARS-CoV-2’s ability to dysregulate the immune system and suppress the immune system, the spike protein itself is very damaging to blood vessel structures as well as red blood cells and platelets themselves.

And so between those two features, the ability to dysregulate the immune system and the ability to cause systemic damage throughout the bloodstream, you have a very dangerous novel virus on your hands.

https://www.cbc.ca/radio/quirks/beyond-long-covid-1.7485888

“There is no such thing as a COVID infection without consequence,” says long COVID researcher, David Putrino[…].

So there is a cumulative effect that can be occurring with each infection.

Early in the pandemic, we actually published a paper where we showed that, even in animal models — when we infected mice with a very, very mild case of SARS-CoV-2 infection — which only caused lung inflammation, we still saw these inflammatory chemicals called chemokines emerging from the infected lungs and starting to attack central nervous system structures such as the spinal cord and the brain.

[…]You know, this is a virus that, once it enters the body, is very capable of entering the bloodstream, creating immune responses that travel all over the body.

It disrupts what we call “interferon signalling,” which is part of the immune system that helps you to fight off infections or latent infections, such as Epstein Barr virus.

Typically our immune system can keep these things suppressed, but when SARS-CoV-2 enters the picture, it starts to cause altered interferon signalling. It causes immune damage and dysregulation.

And suddenly, not only does your body have trouble clearing the SARS-CoV-2 virus itself, but it also starts to have trouble keeping some of these other viruses that have been latent from reactivating and causing problems.

In addition to SARS-CoV-2’s ability to dysregulate the immune system and suppress the immune system, the spike protein itself is very damaging to blood vessel structures as well as red blood cells and platelets themselves.

And so between those two features, the ability to dysregulate the immune system and the ability to cause systemic damage throughout the bloodstream, you have a very dangerous novel virus on your hands.

To be fair, I’m also stateside and, while I knew enough to know not to do it with abandon, I’ve torrented without a VPN at least a handful of times and never got anything from my ISPs in two decades.

Socialist, Guix

Oh, I meant that the muggles being made the throne, rather than other magical creatures, was still genocidal eugenicism (basically, still qualifies, even if I didn’t remember correctly).

But the previous example you bring up is another case of what I was trying to highlight: the books are aware of the low-key prejudice present throughout the society. Both implicitly and explicitly (e.g. Dumbledore’s highlight), it’s aware that less overt forms of prejudice exists.

Which is what makes it never getting addressed, by the end of the books, so…I dunno, notable, in some capacity?

It’d be much more simple if we could just say that the books implicitly argue for the status quo but it’s something more overt, instead. The books seem cognizant and aware of marginalization – both supremacist (à la Voldemort) and social/somewhat-systemic (various examples we’ve brought up) – yet there’s a way in which even this awareness is tamped down to that’s-just-the-way-it-is by not even arguing for it but just by…doing nothing about it. These microaggressions and prejudices are noticed though never confronted while we continue to socialize and interact with these people who express such bigotry and never gets resolved in any meaningful way, by the end.

discover him in this state

It’s the guy in the picture.

People rarely seem to consider this.

Have you tried biking? I like it because it’s so easy to zone out with (and easier on the knees than running).

You can buy a cheap standing bike and watch shows or read books; and, if you go outside to bike, you get the benefit of the sun and trees. If they have rentable electric bikes, those can make the exertion part easier (and, if it feels like cheating, it’s still more exercise than you’d’ve otherwise been getting; plus studies have shown that some people, with electric bikes, ride for longer periods than those who don’t because they’re having so much fun).

It’s definitely not the case; but it’s the excuse Randy gives when people discover him in this state shortly thereafter.

It truly is an encapsulation of ablism that you’re being downvoted regarding keeping things accessible on a post about causing harm to the marginalized.

Voldemort is evil because he wants to be immortal (not because he promotes the ideas of an genocidal eugenicist)

That’s not quite true but the degree that’s tolerated is what makes it odd.

In (I think) the seventh book, the trio is horrified, upon infiltrating the Ministry of Magic, at a statue that the Death Eaters have installed which has wizards sitting on muggles as a throne with the phrase “Magic is Might” (for whatever reason, my brain remembered this as, like, a centaur and an elf and, maybe, a goblin underneath but I think this still qualifies for genocidal eugenicism, nonetheless).

But (as you and others have pointed out) these ideas have kind of tepidly been present throughout wizard society well through the books. Even if we disregard – say – Malfoy’s use of Mudblood and such (as his family was always analogous to supremacist families, anyway): Arthur Weasley’s pretty much not respected by his colleagues for his interest in muggles (which, if we were to actually take themes seriously, could have been an opportunity for Rowling to draw further connections with his monetary class) while those who do respect him kind of just regard it as pointless amusement, the fact that nearly every magical creature exists meaningfully segregated from wizarding society without any exploration of why (even in cases where the text provides it as being a choice by the magical creatures), and other small bits.

Like, perfectly reasonable if you’re trying to represent a realistic society (people have all kinds of prejudices) but Rowling and her protagonists seemingly have no interest in it (or, perhaps more importantly, rooting it out more thoroughly past the overt supremacy of Voldemort).

Explicit, in-your-face bigotry: the books come down hard on but it seems wholly interested in maintaining the status quo, so long as it isn’t disruptive.

Which, like, (considering the author) isn’t surprising but I do find it interesting in the ways in manifests itself.

When do I get to shit in anybody’s mouth‽

It couldn’t be going worse, Keith.

You’re talking about a black art form, with DJ Khaled doing what every hypeman in the history of the genre has done since its inception; there is no context where saying he’s being inappropriate in what he’s doing is not racial.

I promise you, your appeals to “race-baiting” (of all things) as a justification of what’s going on are not putting you on the political side of the spectrum you usually associate yourself with.

I doubt this will be sufficient to not sound like anything I’ve said before but I sincerely and genuinely believe you lack context which you aren’t willing to hear.

For real; I hope it’s mostly just one instance. I haven’t been paying attention to instances but it feels shockingly widespread on Lemmy (but, given lemmy.world’s size, it could just be that).

Thanks for backing me up and keeping me from feeling crazy.

Ah; I thought you were approaching and conversing in good faith. My mistake.

If you’re unfamiliar with the tone policing of “not following proper decorum” (and that’s exactly what “he doesn’t need to be shouting his name on every song” is; it’s not a debate about whether he can: it’s an assertion that that’s not an appropriate way to behave for the setting), then you should probably familiarize yourself.

But, as a person with lived racial experience, I am very much not reaching.

I mean, I’d find it hard to say he’s not, at all, an entertainer?

Like, I feel most people know him from seeing performances of him. He, essentially, performs the role of hypeman, a lot of times.

I certainly wouldn’t disagree he also acts as a business man but I think he does a lot of entertainment-related work, as well.

I mean, that’s always been the refrain around colored entertainers.

To save you what turned into a whole year for me, – if you have anyone else who can help you – tag team applying. I only started to see consistent interviews once my husband started helping and we started not only flooding every listing we could but, also, routinely applying before a lot of people got to them.

Good luck; one of the worst years of my life.

Roughly translated, it means, “We are men.” It’s a French term (as the French were the first to colonize the area) derived from the term “Illiniwek” which was used by the natives there to refer to (in English) the Illinois Confederation, a loosely organized group of 12 to 13 tribes who lived in the Mississippi River Valley.